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authFullName_s : Cédric Le May

Circulating PCSK9 levels are not associated with the severity of hepatic steatosis and NASH in a high-risk population

Matthieu Wargny , Pierre-Henri Ducluzeau , Jean-Michel Petit , Cédric Le May , Sarra Smati , et al.
Atherosclerosis, 2018, 278, pp.82-90. ⟨10.1016/j.atherosclerosis.2018.09.008⟩
Journal articles hal-01945151v1

Role of PCSK9 beyond liver involvement

Bertrand Cariou , Karim Si-Tayeb , Cédric Le May
Current Opinion in Lipidology, 2015, Equipe 5, 26 (3), pp.155--161. ⟨10.1097/MOL.0000000000000180⟩
Journal articles hal-01830980v1
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Plasma PCSK9 concentrations during the course of nondiabetic chronic kidney disease: Relationship with glomerular filtration rate and lipid metabolism

Marion Morena , Cédric Le May , Leila Chenine , Lucie Arnaud , Anne-Marie Dupuy , et al.
Journal of clinical lipidology, 2017, 11 (1), pp.87-93. ⟨10.1016/j.jacl.2016.10.005⟩
Journal articles hal-01763117v1

The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis

Amélie Bonnefond , Loïc Yengo , Cédric Le May , Fréderic Fumeron , Michel Marre , et al.
Diabetologia, 2015, Equipe 5, 58 (9), pp.2051--2055. ⟨10.1007/s00125-015-3659-8⟩
Journal articles hal-01830978v1

Generation of a GPR146 knockout human induced pluripotent stem cell line (ITXi001-A-1)

Lise Bray , Amandine Caillaud , Aurore Girardeau , Murielle Patitucci , Cédric Le May , et al.
Stem Cell Research, 2022, 60, pp.102721. ⟨10.1016/j.scr.2022.102721⟩
Journal articles hal-03869113v1

PAX4 gene variations predispose to ketosis-prone diabetes

Cedric Le May , Franck Mauvais-Jarvis , Stuart Smith , Cédric Le May , Suzanne Leal , et al.
Human Molecular Genetics, 2004, 13 (24), pp.3151-3159. ⟨10.1093/hmg/ddh341⟩
Journal articles hal-03013354v1

Roux-en-Y gastric bypass reduces plasma cholesterol in diet-induced obese mice by affecting trans-intestinal cholesterol excretion and intestinal cholesterol absorption

Claire Blanchard , François Moreau , Audrey Ayer , L. Toque , Damien Garçon , et al.
International Journal of Obesity, 2018, Equipe IV, 42 (3), pp.552--560. ⟨10.1038/ijo.2017.232⟩
Journal articles hal-01833321v1

Beyond LDL: What Role for PCSK9 in Triglyceride-Rich Lipoprotein Metabolism?

Wieneke Dijk , Cédric Le May , Bertrand Cariou
Trends in endocrinology and metabolism: TEM, 2018, Equipe IV, 29 (6), pp.420 - 434. ⟨10.1016/j.tem.2018.03.013⟩
Journal articles hal-01833913v1

Fatty Acids Induce L-CPT I Gene Expression through a PPARα-Independent Mechanism in Rat Hepatoma Cells

Cedric Le May , Cédric Le May , Michèle Caüzac , Claire Diradourian , Dominique Perdereau , et al.
Journal of Nutrition, 2005, 135 (10), pp.2313-2319. ⟨10.1093/jn/135.10.2313⟩
Journal articles hal-03013352v1

FACS-assisted CRISPR-Cas9 genome editing of human induced pluripotent stem cells

Amandine Caillaud , Antoine Lévêque , Aurélie Thédrez , Aurore Girardeau , Robin Canac , et al.
STAR Protocols, 2022, 3 (4), pp.101680. ⟨10.1016/j.xpro.2022.101680⟩
Journal articles hal-04060050v1
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The Tryptophan/Kynurenine Pathway: A Novel Cross-Talk between Nutritional Obesity, Bariatric Surgery and Taste of Fat

Arnaud Bernard , Cédric Le May , Aurélie Dastugue , Audrey Ayer , Claire Blanchard , et al.
Nutrients, 2021, 13 (4), pp.1366. ⟨10.3390/nu13041366⟩
Journal articles hal-03328777v1

Proprotein Convertase Subtilisin Kexin Type 9 Null Mice Are Protected From Postprandial Triglyceridemia

Cedric Le May , Cédric Le May , Sanae Kourimate , Cédric Langhi , Maud Chétiveaux , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (5), pp.684-690. ⟨10.1161/ATVBAHA.108.181586⟩
Journal articles hal-03013340v1

Sleeve Gastrectomy Alters Intestinal Permeability in Diet-Induced Obese Mice

Claire Blanchard , François Moreau , Julien Chevalier , Audrey Ayer , Damien Garcon , et al.
Obesity Surgery, 2017, 27 (10), pp.2590-2598. ⟨10.1007/s11695-017-2670-1⟩
Journal articles hal-01560488v1

PCSK9 Concentrations in Cerebrospinal Fluid Are Not Specifically Increased in Alzheimer's Disease

Hélène Courtemanche , Edith Bigot , Matthieu Pichelin , Béatrice Guyomarch , Claire Boutoleau-Bretonnière , et al.
Journal of Alzheimer's Disease, 2018, Equipe IV, ⟨10.3233/JAD-170993⟩
Journal articles hal-01833920v1
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Effects of proprotein convertase subtilisin kexin type 9 modulation in human pancreatic beta cells function

Stéphane Ramin-Mangata , Aurélie Thedrez , Brice Nativel , Nicolas Diotel , Valentin Blanchard , et al.
Atherosclerosis, 2021, 326, pp.47-55. ⟨10.1016/j.atherosclerosis.2021.03.044⟩
Journal articles hal-03353494v1
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PCSK9 deficiency results in a specific shedding of excess LDLR in female mice only: Role of hepatic cholesterol

Anna Roubtsova , Damien Garçon , Sandrine Lacoste , Ann Chamberland , Jadwiga Marcinkiewicz , et al.
Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2022, 1867 (12), pp.159217. ⟨10.1016/j.bbalip.2022.159217⟩
Journal articles hal-03869056v1
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Generation of an induced pluripotent stem cell line (ITXi012-A) from a patient with genetically determined high-lipoprotein(a) plasma levels

Amandine Caillaud , Lise Bray , Aurore Girardeau , Zoé Begué-Racapé , Lucie Vince , et al.
Stem Cell Research, 2023, 72, ⟨10.1016/j.scr.2023.103205⟩
Journal articles hal-04212298v1

Transintestinal cholesterol excretion in health and disease

Damien Garçon , Jean-Matthieu Berger , Bertrand Cariou , Cédric Le May
Current Atherosclerosis Reports, 2022, 24 (3), pp.153-160. ⟨10.1007/s11883-022-00995-y⟩
Journal articles hal-03869126v1
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Effect of Parathyroidectomy on Metabolic Homeostasis in Primary Hyperparathyroidism

Samuel Frey , Raphaël Bourgade , Cédric Le May , Mikaël Croyal , Edith Bigot-Corbel , et al.
Journal of Clinical Medicine, 2022, 11, ⟨10.3390/jcm11051373⟩
Journal articles hal-03869109v1

PCSK9 Dominant Negative Mutant Results in Increased LDL Catabolic Rate and Familial Hypobetalipoproteinemia

Cedric Le May , Bertrand Cariou , Khadija Ouguerram , Yassine Zaïr , Raphael Guerois , et al.
Arteriosclerosis, Thrombosis, and Vascular Biology, 2009, 29 (12), pp.2191-2197. ⟨10.1161/ATVBAHA.109.194191⟩
Journal articles hal-03013337v1
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Letter From Le May and Cariou Regarding Article, "Proprotein Convertase Subtilisin Kexin Type 9 Promotes Intestinal Overproduction of Triglyceride-Rich Apolipoprotein B Lipoproteins Through Both Low-Density Lipoprotein Receptor-Dependent and -Independent Mechanisms

Cédric Le May , Bertrand Cariou
Circulation, 2015, Equipe 5, 131 (18), pp.e427--e427. ⟨10.1161/CIRCULATIONAHA.114.011697⟩
Journal articles hal-01830973v1

Nutritional biomarkers and heart failure requiring hospitalization in patients with type 2 diabetes: the SURDIAGENE cohort

Matthieu Wargny , Mikaël Croyal , Stéphanie Ragot , Elise Gand , David Jacobi , et al.
Cardiovascular Diabetology, 2022, 21 (1), pp.101. ⟨10.1186/s12933-022-01505-9⟩
Journal articles hal-03869068v1

Plasma apolipoprotein concentrations and incident diabetes in subjects with prediabetes

Mikaël Croyal , Matthieu Wargny , Kevin Chemello , Chloé Chevalier , Valentin Blanchard , et al.
Cardiovascular Diabetology, 2022, 21 (1), pp.21. ⟨10.1186/s12933-022-01452-5⟩
Journal articles hal-03869138v1
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In vivo evidence for transintestinal cholesterol efflux in patients with complete common bile duct obstruction

François Moreau , Claire Blanchard , Christophe Perret , Laurent Flet , Frédéric Douane , et al.
Journal of clinical lipidology, 2019, 13 (1), pp.213-217.e1. ⟨10.1016/j.jacl.2018.09.010⟩
Journal articles hal-02429506v1

Taste-Driven Responsiveness to Fat and Sweet Stimuli in Mouse Models of Bariatric Surgery

Aurélie Dastugue , Cédric Le May , Séverine Ledoux , Cindy Le Bourgot , Pascaline Delaby , et al.
Biomedicines, 2022, Special Issue Animal Models of Human Pathology: Revision, Relevance and Refinements, 10 (4), pp.741. ⟨10.3390/biomedicines10040741⟩
Journal articles hal-03869074v1
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Bile acids associate with glucose metabolism, but do not predict conversion from impaired fasting glucose to diabetes

Oscar Chávez-Talavera , Matthieu Wargny , Matthieu Pichelin , Amandine Descat , Emmanuelle Vallez , et al.
Metabolism, 2020, 103, pp.154042. ⟨10.1016/j.metabol.2019.154042⟩
Journal articles inserm-02869470v1

Control of Gene Expression by Fatty Acids

Cedric Le May , Jean-Paul Pégorier , Cédric Le May , Jean Girard
Journal of Nutrition, 2004, 134 (9), pp.2444S-2449S. ⟨10.1093/jn/134.9.2444S⟩
Journal articles hal-03013355v1

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension

Jean-Mathieu Berger , Nathalie Vaillant , Cédric Le May , Carolina Calderon , Jeremy Brégeon , et al.
Atherosclerosis, 2015, Equipe 2 Equipe 5, 239 (1), pp.252--259. ⟨10.1016/j.atherosclerosis.2015.01.012⟩
Journal articles hal-01830594v1
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Unexpected metabolic disorders induced by endocrine disruptors in Xenopus tropicalis provide new lead for understanding amphibian decline

Christophe Regnault , Marie Usal , Sylvie Veyrenc , Karine Couturier , Cécile Batandier , et al.
Proceedings of the National Academy of Sciences of the United States of America, 2018, Equipe IV Therassay, 115 (19), pp.E4416-E4425. ⟨10.1073/pnas.1721267115⟩
Journal articles hal-01833911v1

E2F1 inhibits circulating cholesterol clearance by regulating Pcsk9 expression in the liver

Qiuwen Lai , Albert Giralt , Cédric Le May , Lianjun Zhang , Bertrand Cariou , et al.
JCI Insight, 2017, Equipe IV, 2 (10), ⟨10.1172/jci.insight.89729⟩
Journal articles hal-01828864v1