%0 Journal Article %T Vitamin D and chronic diseases : the current state of the art %+ Laboratoire de Psychologie des Pays de la Loire (LPPL) %+ Medical University Graz %+ Recordati AG %A Muscogiuri, Giovanna %A Altieri, Barbara %A Annweiler, Cédric %A Balercia, Giancarlo %A Pal, H. B. %A Boucher, Barbara J. %A Cannell, John J. %A Foresta, Carlo %A Grübler, Martin R. %A Kotsa, Kalliopi %A Mascitelli, Luca %A März, Winfried %A Orio, Francesco %A Pilz, Stefan %A Tirabassi, Giacomo %A Colao, Annamaria %< avec comité de lecture %J Archives of Toxicology %V 91 %N 1 %P 97-107 %8 2017 %D 2017 %R 10.1007/s00204-016-1804-x %K Vitamin D %K Musculoskeletal disorders %K Cancer %K Cardiovascular diseases %K Dementia %K Autism %K Diabetes mellitus %K Hypogonadism %K Fertility %K PCOS %K Environment %K Lifestyle %K Endometriosis %Z Cognitive science/PsychologyJournal articles %X The objective was to provide the current state of the art regarding the role of vitamin D in chronic diseases (osteoporosis, cancer, cardiovascular diseases, dementia, autism, type 1 and type 2 diabetes mellitus, male and female fertility). The document was drawn up by panelists that provided their contribution according to their own scientific expertise. Each scientific expert supplied a first draft manuscript on a specific aspect of the document’s topic that was subjected to voting by all experts as “yes” (agreement with the content and/or wording) or “no” (disagreement). The adopted rule was that statements supported by ≥75 % of votes would be immediately accepted, while those with \textless25 % would be rejected outright. Others would be subjected to further discussion and subsequent voting, where ≥67 % support or, in an eventual third round, a majority of ≥50 % would be needed. This document finds that the current evidence support a role for vitamin D in bone health but not in other health conditions. However, subjects with vitamin D deficiency have been found to be at high risk of developing chronic diseases. Therefore, although at the present time there is not sufficient evidence to recommend vitamin D supplementation as treatment of chronic diseases, the treatment of vitamin D deficiency should be desiderable in order to reduce the risk of developing chronic diseases. %G English %L hal-03287641 %U https://nantes-universite.hal.science/hal-03287641 %~ UNIV-NANTES %~ UNIV-ANGERS %~ LPPL %~ NANTES-UNIVERSITE %~ UNIV-NANTES-AV2022 %~ TEST3-HALCNRS